Research

*Completed research projects are marked with a black line.

Digital Biomarker

VoxGnosis

The early diagnosis and subtype classification of Alzheimer's disease based on digitalized speech signal

Digital Biomarker

OldDigitalPlatform

Development and clinical application of digital therapeutic devices UX, untact clinical cloud platforms and RWE technologies based on the brain and body of the elderly

BioMarker

BloodBioMarker

Discovery of effective bacterial strains regulating the inflammatory response of microglia and identification of underlying mechanism through intestinal microbiome analysis of Alzheimer’s disease patients

Biomarker

Microbiota

Study of dementia specific Microbiome, lipidome and microRNA profile

Biomarker

DementiaBank

한국형 치매(K-dementia) 통합 빅데이터 허브 시스템 구축

Clinical Trials

Mediforum

To evaluate the safety and efficacy of PM012 tablets for Alzheimer’s disease, dose-finding study will be performed on phase 2b, and the established dose will be used for the non-inferiority phase 3 trial to evaluate the investigational product’s safety and efficacy: Double blind, randomized, active drug comparative, multi-center, parallel-group clinical trial

Clinical Trials

KBASE

Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer’s disease (K-BASE)

Clinical Trials

KBASE2

Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer’s disease 2 (K-BASE2)

Clinical Trials

ESCALADE

A Multi-center, Randomized, Double-blind, Placebo-controlled, Phase IV Trial to Evaluate the Efficacy and Safety of Choline Alfoscerate Compared to Placebo in Patients With degenerative Mild Cognitive Impairment

Clinical Trials

BAN2401

A Placebo-Controlled, Double-Blind, Parallel-Group, 18-Month Study With an Open-Label Extension Phase to Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimer’s Disease

Clinical Trials

E2609

A Placebo-Controlled, Double-Blind, Parallel-Group, 24-Month Study to Evaluate the Efficacy and Safety of E2609 in Subjects with Early Alzheimer’s Disease

Clinical Trials

KREATE

Korean Registry for Activating Trial on Dementia (KReAT-D)

Brain

Neurofolio

Post-market surveillance study of the Neurofolio

Brain

COVID-19

The Effects of COVID-19 Quarantine on the Cognitive and Behavioral Symptoms of Dementia

Brain

MRIRisk

대기오염과 알츠하이머병의 관계 규명 연구

Digital Biomarker

EmoRobot

Developing mirroring expression based interactive robot technique by non-contact sensing and recognizing human intrinsic parameter for emotion healing through heart-body feedback

Digital Biomarker

ARETE

20년 AI 음성 선별 모델 개발을 위한 음성기반 조기 치매선별 연구용역

Digital Biomarker

FaceOff

Emotional recovery of patients with patients using facial emotional feedback program using camera

Digital Biomarker

MCIExam

Standardization of neuropsychological test for dementia classification

Digital Biomarker

Famenity

Verification of the Effects of Intervention Program on Improving Mental Health of patients with Post-traumatic Stress Disorder

Clinical Trials

Crenezumab-CREAD

A phase III, multicenter, randomized, double blind, placebo controlled, parallel group, efficacy and safety study of crenezumab in patients with prodromal to mild alzheimer’s disease

Brain

Neurofolio

Post-market surveillance study of the Neurofolio

Brain

COVID-19

The Effects of COVID-19 Quarantine on the Cognitive and Behavioral Symptoms of Dementia

Brain

MRIRisk

대기오염과 알츠하이머병의 관계 규명 연구

Digital Biomarker

VoxGnosis

The early diagnosis and subtype classification of Alzheimer's disease based on digitalized speech signal

Digital Biomarker

OldDigitalPlatform

Development and clinical application of digital therapeutic devices UX, untact clinical cloud platforms and RWE technologies based on the brain and body of the elderly

Digital Biomarker

EmoRobot

Developing mirroring expression based interactive robot technique by non-contact sensing and recognizing human intrinsic parameter for emotion healing through heart-body feedback

Digital Biomarker

ARETE

20년 AI 음성 선별 모델 개발을 위한 음성기반 조기 치매선별 연구용역

Digital Biomarker

FaceOff

Emotional recovery of patients with patients using facial emotional feedback program using camera

Digital Biomarker

MCIExam

Standardization of neuropsychological test for dementia classification

Digital Biomarker

Famenity

Verification of the Effects of Intervention Program on Improving Mental Health of patients with Post-traumatic Stress Disorder

BioMarker

BloodBioMarker

Discovery of effective bacterial strains regulating the inflammatory response of microglia and identification of underlying mechanism through intestinal microbiome analysis of Alzheimer’s disease patients

Biomarker

Microbiota

Study of dementia specific Microbiome, lipidome and microRNA profile

Biomarker

DementiaBank

한국형 치매(K-dementia) 통합 빅데이터 허브 시스템 구축

Clinical Trials

Mediforum

To evaluate the safety and efficacy of PM012 tablets for Alzheimer’s disease, dose-finding study will be performed on phase 2b, and the established dose will be used for the non-inferiority phase 3 trial to evaluate the investigational product’s safety and efficacy: Double blind, randomized, active drug comparative, multi-center, parallel-group clinical trial

Clinical Trials

KBASE

Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer’s disease (K-BASE)

Clinical Trials

KBASE2

Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer’s disease 2 (K-BASE2)

Clinical Trials

ESCALADE

A Multi-center, Randomized, Double-blind, Placebo-controlled, Phase IV Trial to Evaluate the Efficacy and Safety of Choline Alfoscerate Compared to Placebo in Patients With degenerative Mild Cognitive Impairment

Clinical Trials

BAN2401

A Placebo-Controlled, Double-Blind, Parallel-Group, 18-Month Study With an Open-Label Extension Phase to Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimer’s Disease

Clinical Trials

E2609

A Placebo-Controlled, Double-Blind, Parallel-Group, 24-Month Study to Evaluate the Efficacy and Safety of E2609 in Subjects with Early Alzheimer’s Disease

Clinical Trials

KREATE

Korean Registry for Activating Trial on Dementia (KReAT-D)

Clinical Trials

Crenezumab-CREAD

A phase III, multicenter, randomized, double blind, placebo controlled, parallel group, efficacy and safety study of crenezumab in patients with prodromal to mild alzheimer’s disease